Current Issue : October-December Volume : 2026 Issue Number : 4 Articles : 5 Articles
Stretchable sensors are widely used in wearable devices and flexible electronics for their unique advantages in flexibility. However, assembling and integrating stretchable devices face challenges due to the low deformation tolerance of soft-rigid connections. Moreover, in manufacturing flexible electronics, convenient and reversible connections like soldering that enable on-demand replacement of soft units remain unavailable. Here, we report a supramolecular conductive adhesive (SCA) based on a nanocomposite of thermoresponsive polymers and conductive fillers. SCA applies to diverse substrates such as plastics, rubbers, and metals with robust mechanical connections and stable anisotropic electrical conductivity. SCA-connected stretchable systems exhibit excellent tensile tolerance, with Au@SEBS connected to rigid units achieving mechanical stretchability exceeding 300% strain and electrical stretchability over 80% strain. SCA is also directly applicable to traditional electronic components, with reusability resembling traditional solders. At 80◦C, SCA can be reversibly detached, and without renewal, SCA maintains its original connection strength and electrical stretchability over 5 reuse cycles. The reversible connections enable on-demand replacement of stretchable units in flexible electronics for device repair or customization. This reduces the cost of flexible electronics and significantly extends their overall service life, holding broad potential in the more sustainable production of flexible electronics....
Oxaliplatin serves as a cornerstone chemotherapeutic agent for solid tumors (e.g., colorectal and gastric cancers); however, its associated dose-limiting peripheral neuropathy (OIPN) severely compromises patients’ quality of life and treatment completion rates. OIPN manifests as acute cold-induced paresthesia and chronic cumulative sensory neuropathy, with complex, incompletely elucidated pathophysiological mechanisms. This review systematically summarizes the core molecular mechanisms of OIPN, focusing on: (1) sensitization of transient receptor potential vanilloid/ankyrin channels (TRPV1/TRPA1), (2) dysregulated expression and function of voltage-gated sodium channels (NaV1.7, NaV1.8), and (3) the critical role of p38 mitogen-activated protein kinase (p38-MAPK) pathway activation in neuronal hyperexcitability and pain signal transduction within dorsal root ganglion (DRG) sensory neurons. Additionally, we delve into dynamic alterations of the DRG immune microenvironment (notably macrophages and T cells) during OIPN initiation/progression, as well as their crosstalk with neurons. To address the clinical dilemma of limited effective preventive/therapeutic approaches, this review outlines limitations of current strategies and highlights the advantages of nanotechnology-based drug delivery systems in enhancing neuroprotective agent bioavailability and enabling targeted delivery. Finally, we hypothesize the integration of salidroside (a natural product with anti-inflammatory/antioxidant properties) with nanotechnology, and propose leveraging cutting-edge tools (spatial transcriptomics, single-cell RNA sequencing) to elucidate its potential mechanistic action in OIPN—providing a theoretical hypothesis and exploratory research directions for precision OIPN prevention and treatment, in the absence of any empirical evidence for salidroside’s efficacy in this specific pathological context....
Optical superabsorbers use nanostructures to achieve very high levels of optical absorptivity and emissivity across a wide range of wavelengths and angles of incidence. This makes them ideally suited for a wide range of applications in energy management and scavenging, including architectural and domestic heating and cooling. These absorbers feature absorptivity and emissivity values that are typically within a small fraction from the ideal Planck blackbody equation. Here, vertically aligned multiwalled carbon nanotube forest superabsorbers were grown on sapphire to determine their optical properties, particularly in the infrared. The propagation of electromagnetic radiation along the forests was modeled in order to reveal the absorption mechanisms that lead to such high levels of absorption, which up to now, remain poorly understood. The model suggests the absorption mechanism is strongly linked to the in-plane electrical conductivity of the nanotubes and is largely independent of the through-plane conductivity. This is counterintuitive as the through-plane conductivity is parallel to the electric-field vector of the incident wave. The radiative heating/cooling performance of such superabsorber coupled to a hypothetical thermoelectric device is also modeled to assess its environmental capacity for heat management within a domestic/office setting....
Nanotechnology is a rapidly growing, transformative approach in the field of male reproductive health, addressing dire challenges connected with infertility. This review explores the application of nanotechnology in enhancing sperm selection and processing, which are vital for improving reproductive outcomes in assisted reproductive technologies (ART). Traditional methods, such as swim-up assay and density gradient centrifugation, often yield variable recovery rates and may not be efficient with poor sperm samples. In contrast, innovative techniques utilizing nanoparticles, especially magnetic-activated cell sorting (MACS), demonstrate superior efficacy in selective isolation of viable sperm by targeting specific biomarkers. The unique properties of nanoparticles, including tunable size and surface charge, enhance their binding capabilities, thereby improving the precision of sperm selection.C Additionally, advancements in assisted reproductive technologies, showcase the potential of nanoparticles in sperm transport and gamete preservation. Despite the potential benefits, challenges remain, including the need for standardized protocols and addressing safety concerns associated with nanoparticle use. This review underscores the necessity for future studies to fully harness the potential of nanotechnology in overcoming male infertility, ultimately contributing to improved ART success rates and better reproductive health outcomes....
Carbon nanotube field-effect transistors (CNT FETs) hold great promise for extending Moore’s Law, yet their performance is critically limited by excessive off-state leakage, caused by band-to-band tunneling (BTBT) in narrow bandgap CNT channels. In this work, we overcome this long-standing bottleneck by introducing a co-design strategy that integrates a small-diameter HiPco CNT channel with a novel asymmetric gate architecture. This approach strategically reshapes the channel electrostatics to simultaneously suppress the gate-induced drain leakage (GIDL) effect and preserve excellent carrier transport. The efficacy of this strategy is rigorously validated through calibrated technology computeraided design (TCAD) simulations for both NMOS and PMOS operation, demonstrating an ultralow off-current of 10 fA/μm, an on-current of 1.08 mA/μm, and a record on–off ratio of 1.1 × 1011 for back-gated CNTFETs at the 90 nm node. The design exhibits outstanding scalability: at the scaled 28 nm node with a supply voltage of 0.7 V, the PMOS device achieves 3 mA/μm on-current and 6 pA/μm off-current, maintaining an on–off ratio of 5 × 108. This work establishes a scalable pathway toward femtoampere-level CNT CMOS, addressing the static power challenge in future nano-electronics....
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